Proline Plus mechanical pipettes by Sartorius Biohit present a robust and versatile range of laboratory liquid handling tools, spanning volumes from as small as 0.1 µL up to 10,000 µL (10 mL). This wide volume range makes them applicable for diverse laboratory tasks, from delicate small-volume biochemical assays to larger sample preparations. The pipettes are engineered with high chemical and UV resistance, ensuring durability even in rigorous lab environments. They employ an Optiload tip loading mechanism, especially in multichannel models, which facilitates easy, low-force tip attachment and ejection to minimize user fatigue and risk of repetitive strain injuries (RSI) such as carpal tunnel syndrome. Furthermore, these pipettes come with color-coded volume displays matching tip trays for error reduction and improved workflow efficiency. They include Safe-Cone filters that prevent aerosol and fluid contamination inside the pipette, contributing to reliable and consistent results. Notably, their design supports both right- and left-handed users and they are fully autoclavable for sterilization convenience, with only two to three parts for easy maintenance. Prices vary by volume and specification, with some examples around $170 to over $570 per unit. The product also carries a 2-year warranty, reflecting confidence in its build quality and longevity.

The ergonomic design of Proline Plus pipettes focuses on minimizing pipetting forces through features like a comfortable handle, ergonomic finger support, and a balanced grip that reduces effort during liquid aspiration and dispensing. These design elements directly contribute to reduced hand strain and fatigue, supporting prolonged use in busy laboratory settings. The pipettes allow click-stop volume setting where users can easily adjust volumes with tactile clicks, helping prevent volume-setting errors. The wide range of available pipettes includes fixed-volume types, which are especially valuable in standardized testing or educational settings where fixed sample volumes avoid measurement variability. Multichannel pipettes feature a spring-loaded tip cone system with the Optiload mechanism, offering equal force distribution for tip loading and ensuring perfect seals on all channels, essential for reproducible multi-sample handling. Additionally, the internal components are thermally insulated to improve accuracy by minimizing the effects of hand heat on liquid volume.

Maintenance and calibration of Proline Plus pipettes have been simplified with a user-friendly approach; only three parts need disassembly for cleaning or servicing, and no specialized tools are required. This not only extends the life of the pipette but reduces downtime and costs associated with laboratory instrument upkeep. The pipettes can be recalibrated by users themselves using included calibration tools or through professional services. Safe-Cone filters are replaceable and crucial to maintaining contamination-free pipetting, particularly after over-aspiration or when liquid contacts filters. The Autoclavable feature enhances lab hygiene protocols by allowing sterilization without lengthy disassembly or damage risks. These characteristics make the Proline Plus suitable for medium to heavy use in both professional research labs and teaching environments.

In summary, the Proline Plus mechanical pipettes stand out in the laboratory pipetting world by offering an exceptional combination of durability, ergonomic design, precision, and user-centric features. Their broad volume range, ergonomic advances, contamination prevention mechanisms, and ease of maintenance make them ideal for a wide range of laboratory applications, providing both comfort and accuracy for researchers and students alike. Examples of their practical use include precise dispensing of enzymes in PCR, controlled dilution of reagents in chemical analyses, and repetitive sampling in microbiology workflows where volume consistency and user comfort are paramount.

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